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Women using so much Botox it's stopped working: Users develop antibodies making treatment less effective

Publication: Mail Online | 28/04/2013

MediZen's Dr. Eccleston, was featured in the Daily Mail on 28th April 2013, featured in the article, Women using so much Botox it's stopped working: Users develop antibodies making treatment less effective. Have a look at the full article here at the Daily Mail website.

Women using so much Botox it's stopped working: Users develop antibodies making treatment less effective.

It is the £200-a-time beauty treatment many women swear by to smooth out their wrinkled foreheads and crow’s feet.

But those relying on Botox to hold back the years could be wasting their money – because they are becoming immune to the injections, warn scientists.

They say the drug, a type of neurotoxin, is failing to freeze the facial muscles of some patients as well as it did before, or for as long.

Many women are even developing antibodies to some types of the treatment, meaning it stops working altogether.

A review by German researchers, published in the Journal of Neural Transmission, found that one in 200 Botox users developed antibodies, making the treatment less effective over time.

Patients who needed larger doses – including those prescribed it for medical reasons to treat spasms or sweating – were more likely to stop responding, the research found.

Other scientists, writing in the British Medical Journal’s online forum Open, revealed that repeated injections ‘can trigger an immune response... which might lead to non-responsiveness to treatment’.

Dr David Eccleston, of the MediZen Clinic in Birmingham, who trains others how to use Botox, said some unscrupulous clinics could be diluting it with too much saline solution to make supplies go further.